ea0056p733 | Endocrine tumours and neoplasia | ECE2018
Wierinckx Anne
, Delgrange Etienne
, Vasiljevic Alexandre
, Jouanneau Emmannuel
, Lachuer Joel
, Trouillas Jacqueline
, Raverot Gerald
Introduction: Various tumours have a worse prognosis in male than in female. This is also true for lactotroph tumours. Indeed it is known that aggressive and malignant tumours, resistant to dopamine agonists, are more frequent in male than female and are associated to lower ESR1 expression.Objectives: Our aims are to study the genes differentially expressed and the chromosomic alterations in lactotroph tumours between male and female and their relationsh...